The movie begins with the marriage of John and Regina at a church. The marriage is an arranged one, to which both have consented reluctantly to make their parents happy. After the marriage, they live together as strangers in their apartment, where the neighbours are upset with John who comes home drunk every night, which he does deliberately to annoy Regina. Eventually, Regina applies for a transfer to Australia to stay away from John.

One night, Regina falls down with fits. John calls an ambulance and takes Regina to the hospital, where he is unable to respond to the doctor's queries about Regina's age and medical history. When he goes to apologise to the doctor later on, he is told that it is important to know about his wife's health, even if he dislikes her. John then asks Regina about her health issues, and she reveals that she had fits twice in the past. The movie sees its first flashback as she explains her past and the love of her life, Surya.

While in college, she falls in love with Surya, who works in the call center of a mobile company. Surya gets selected for airline cabin-crew training in the US. They decide to inform their parents about their love but his father objects to their relationship and hence they decide to get married without informing their parents. On the designated day, Surya fails to show up at the register office for the wedding. Regina's father James feels sorry for his daughter and takes Regina to Surya's house, where they learn that Surya has already left for the US. A few days later, Regina gets a call from Surya's friend Aiyappan, saying that Surya had committed suicide in the US. In her shock, she suffers fits for the first time.

Upon hearing this story, John begins to like Regina and now has immense respect for her. Regina, however, continues to treat John with scant respect, until one day, when Sarathy comes to their flat and reveals John's past in the second major flashback of the movie. John had fallen in love with Keerthana, and they eventually get married. On the day after their marriage, Keerthana is hit by a car while crossing the road, and she dies in front of John. This leaves John heartbroken and he vows not to marry another girl again. 4 years later, Sarathy consoles him and convinces him to marry again. This brings back the events that occurred in the beginning of the film with John wedding Regina.

Regina now begins to like John. Though they like each other, they never reveal it to each other. Finally, on John's birthday, Regina gives John a gift and insists that he open it alone, but John never opens the gift as he thinks that Regina is only pretending to be affectionate in front of her father.

Regina's request for the transfer to Australia is approved. When she tells John, while he was having a beer that she bought for him, he asks her to go ahead with her plans, as he thinks that she was trying to bribe him with the beer to get him to agree to a divorce, while she actually wanted to express her love for him.

John drops off Regina at the airport. When he is about to leave the airport, he gets a call from Regina, who tells him that she saw Surya at the emigration counter. John rushes off to meet Surya and tries to get him to accept Regina. Surya says that he was forced to leave by his father and that he faked his suicide so that Regina would get over him. Surya lies to John saying that he is now happily married and tells John that one cannot always marry the girl he loves, but should always love the girl he marries. As he leaves, he glances at the ring in his hand, which was gifted to him by Regina, showing that Surya will always live with the memories of their relationship and never marry another girl.

Regina, who is terribly angry, slaps John as she never wanted to get back with Surya, as that was the past. Regina throws the gift that John never opened. When he opens it he finds the words "Let's begin our new Life". John and Regina realise their love for each other and begin their life together.